Kidney failure reversed without any drugs in mice – could humans be next?

Scientists have reversed acute kidney injury in mice by genetically altering ceramide processing, preventing damage to mitochondria. This drug-free approach resulted in completely normal kidney function and intact mitochondria even under extreme stress. The findings suggest ceramides are a key factor in kidney damage and offer a new avenue for treatment.

Kidney failure reversed without any drugs in mice – could humans be next?
Scientists have reversed acute kidney injury in mice by genetically altering ceramide processing, preventing damage to mitochondria. This drug-free approach resulted in completely normal kidney function and intact mitochondria even under extreme stress. The findings suggest ceramides are a key factor in kidney damage and offer a new avenue for treatment.