IIT Bombay–Monash team cracks TB mystery, finds lipid wall that helps bacteria outsmart drugs
Scientists have uncovered why tuberculosis bacteria evade antibiotics by entering a dormant state. Researchers found that dormant TB bacteria develop a thicker, more rigid outer membrane, acting as a barrier that prevents drugs from entering. This discovery suggests combining existing antibiotics with molecules that weaken this membrane could significantly boost treatment effectiveness against the persistent disease.
Scientists have uncovered why tuberculosis bacteria evade antibiotics by entering a dormant state. Researchers found that dormant TB bacteria develop a thicker, more rigid outer membrane, acting as a barrier that prevents drugs from entering. This discovery suggests combining existing antibiotics with molecules that weaken this membrane could significantly boost treatment effectiveness against the persistent disease.
